The 49ers were 4-11 when Trent Williams missed games entering the season. They went 1-6 last season, as his injury derailed the offense. Williams started last week, but went out after one play. The 49ers proceeded to score 42 points and win the game. Pleasants was not perfect, but he held it down and replaced someone who was deemed irreplaceable.

The 49ers will need Bethune and Dee Winters to anchor this defense, while the 49ers hope for a miraculous return to action from Fred Warner. In a game where not much defense was played, Bethune bounced back on Sunday night, and that’s a great sign for the 49ers and their defense.

The 49ers, backed up in their own end zone, saw the discombobulation from the Bears and it was a good call by 49ers head coach Kyle Shanahan letting things play out, but it turns out some players went off-script from what defensive coordinator Robert Saleh dialed up.

After the conclusion of Sunday's thrilling matchup between the 49ers and Bears, we now know the full Week 18 schedule to conclude the NFL's 2025 regular season.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

The Seahawks made some important roster moves ahead of their do-or-die regular season finale against the 49ers. Read more here.

The San Francisco 49ers made a roster move on Saturday that spells trouble for the Week 17 status of superstar tight end George Kittle, who is questionable to play in Week 17 due to an ankle injury.

The San Francisco 49ers defeated the Chicago Bears on Sunday night, but they still fell in the Week 18 power rankings.