Sam Farmer makes his picks and predictions for the final week of the NFL regular season, with the 49ers beat the Seahawks and the Steelers prevailing.

SEATTLE -- The San Francisco 49ersbeat the Seattle Seahawks, 17-13,in an NFL Week 1 matchup on Sunday. The Seahawks started a new era with Sam Darnold as their starting quarterback, while the 49ers and QB Brock Purdy looked to get back on track after ...

Seattle and San Francisco will decide the NFC West in Week 18. Check our NFL odds series for the Seahawks-49ers prediction and pick.

San Francisco 49ers defensive coordinator Robert Saleh was clear about the issues that would be created if he used man-to-man coverage against Seattle's prolific Jaxon Smith-Njibga.

Week 18 is set with the 49ers hosting the Seattle Seahawks on Saturday, January 3 at 5 p.m. PT at Levi’s® Stadium on ABC and ESPN, with the NFC West title and the conference’s No. 1 seed on the line.

Nick Wright unveils his NFL Tiers going into Week 18 and 2026, featuring the Jacksonville Jaguars, Buffalo Bills and San Francisco 49ers.

Sunday's division-deciding Week 18 clash between the Seattle Seahawks and San Francisco 49ers kicks off with trash talk from rival CB.

Defeating the Chicago Bears meant that the San Francisco 49ers would get to play for the No. 1 seed and NFC West title against the Seattle Seahawks in the seaso

Despite their mountain of injury issues this season, the San Francisco 49ers find themselves within reach of an NFC West title and the No. 1 overall seed in the NFC heading into week 18. The Niners are hosting the Seattle Seahawks on Saturday, Jan. 3, the winner of which will claim both of those honors.

After a wild back-and-forth affair with the Chicago Bears this past Sunday that saw the San Francisco 49ers maintain control of their own destiny with a 42-38 victory, Kyle Shanahan & Co. are now set for a winner-take-all Week 18 showdown with the Seattle Seahawks this Saturday night that will determine both the NFC West and the No.