Late amniocentesis demonstrates a 22.9% overall genetic diagnostic yield, with 2.4 times higher yield for fetuses with multiple organ system anomalies (36.4%) vs single organ system anomalies (15.3%).
Traditionally, chorionic villus sampling (CVS) has been used for diagnosis of genetic abnormality at an earlier gestational age than amniocentesis. More recently, interest has been growing in using ...
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