For cancer cells to metastasize, they must first break free of a tumor's own defenses. Most tumors are sheathed in a protective "basement" membrane -- a thin, pliable film that holds cancer cells in ...

Studies by scientists at Massachusetts Institute of Technology (MIT), Beijing Normal University, and the University of California, San Diego (UCSD) have generated new insights into the elastic ...

Ultrastructural studies of centipede and other myriapod ovaries reveal direct soma-germline contact across the basement membrane, a structure typically regarded as a cellular barrier. A new study by ...

Scientists at Duke University say they made the first time-lapse movies of the sheet-like latticework that surrounds and supports most animal tissues. A thin layer of extracellular matrix known as the ...

Basement membrane, a specialized ECM that underlies polarized epithelium of eumetazoans, provides signaling cues that regulate cell behavior and function in tissue genesis and homeostasis. A collagen ...

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body. In particular, ...

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body. In particular, ...

Light-up proteins in the sheet-like matrix that encases tissues offer new toolkit for studying everything from kidney disease to aging. Duke University researchers have made the first time-lapse ...

Engineers have characterized the properties of the protective membrane around tumors and found that this lining may be a good target for therapies to prevent metastasis. For cancer cells to ...

Matrix metalloproteinases (MMPs) contribute to the breakdown of tissue structures such as the basement membrane, promoting tissue fibrosis. Here we developed an electrospun membrane biofunctionalized ...