In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's powerful ...

Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...

BoNT/Aintoxication of LAN5 cells induces massive tRF changes. (A) Experimental design: 2×106 LAN5 cells/well were intoxicated by 10,000 MsLD50/mL BoNT/A, and small RNA-seq profiles from these cells ...

Please provide your email address to receive an email when new articles are posted on . Some botulinum toxin type A injection formulations have a faster onset, whereas others were shown to last longer ...

Please provide your email address to receive an email when new articles are posted on . Injections yielded significant improvements in visual analog scale pain and Quick-DASH score, as well as skin ...

Botulinum neurotoxins (BoNTs) are a family of highly potent proteins produced primarily by Clostridium species. These toxins induce botulism, a severe paralytic illness resulting from their ability to ...

The use of toxin botulinum-A is one of the most rapidly growing areas in cosmetic dermatology. There is always news about this incredible substance. There are new indications, new techniques, and new ...

Botulinum toxin (BoNT), often referred to as a “miracle poison,” is one of the deadliest biological substances known to man. 1 BoNT is a neurotoxin produced by Clostridium botulinum. A rod-shaped ...

Botulinum toxin type A (BTX-A) has emerged as a promising agent in both scar management and wound healing. By inducing temporary muscular paralysis, BTX-A reduces tension across wound edges, thereby ...