New research findings add further clarity to a question that has polarized the cystic fibrosis (CF) research community. It is well established that people with cystic fibrosis have two faulty copies ...

Researchers studying the root cause of cystic fibrosis have made a major advance in our understanding of silent gene changes with implications for the complexity of cystic fibrosis. Cystic fibrosis is ...

The drug is a small molecule with a novel mechanism of action, say David Bedwell, Ph.D., and Steven Rowe, M.D., MSPH, co-senior authors. Bedwell is professor and chair of the University of Alabama at ...

Cystic fibrosis is a life-limiting disease that is caused by defective or deficient cystic fibrosis transmembrane conductance regulator (CFTR) protein activity. Phe508del is the most common CFTR ...

Edited By: Karen Young Kreeger C.L. Ward, S. Omura, R.R. Kopito, "Degradation of CFTR by the ubiquitin-proteasome pathway," Cell, 83:121-7, 1995. (Cited in nearly 50 publications as of March 1997) ...

When UNSW Associate Professor Shafagh Waters explains cystic fibrosis (CF) to the children she works with, she asks them to imagine what is happening inside their own bodies. "I tell them to picture ...

January 12, 2016 CHAPEL HILL, NC - It is well established that people with cystic fibrosis (CF) have two faulty copies of the CFTR gene, but debate continues on the question of whether certain ...

Cystic fibrosis is a common life-shortening inherited disease that affects over 70,000 people worldwide, the majority of whom are children and young adults. Individuals living with cystic fibrosis ...

Researchers studying the root cause of cystic fibrosis have made a major advance in our understanding of silent gene changes with implications for the complexity of cystic fibrosis. The findings are ...