The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by ...
Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control ...
New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...
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Mapping 'dark' regions of the genome illuminates how cells respond to their environment
"Only 1%–2% of our genome encodes for genes. The other 98% of the genome clearly plays an important role in shaping cell identity, response to the environment, and susceptibility to disease, but until ...
Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...
How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals danger. When the sun shines on your skin, what does it hit? When it causes a ...
Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...
Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...
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