Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

A wave of recent neuroscience research has identified specific molecular and cellular mechanisms through which alcohol disrupts signaling between brain cells, offering a sharper picture of how ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Every multicellular organism, from tiny worms to humans, elephants, and whales, needs a way for their cells to connect with each other to form tissues, organs, and organize their overall body plan.

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, ...

Severe bacterial pneumonia remains a major cause of death in critically ill patients, largely due to impaired early immune responses. New research reveals that butyric acid, a metabolite produced by ...

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet ...

Researchers show that pharmacological activation of hypoxia signaling improves metabolism, limits fat accumulation, and ...