Replication timing (RT), the temporal order in which genomic regions replicate, is considered a functional feature of multiple cellular processes and chromatin organization. Two approaches to measure ...

In the above experiments, most cells were in S phase, as they were released from a thymidine-induced G1/S arrest. To determine whether DNA replication was required for induction of the DNA damage ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

NASA astronaut Nick Hague runs an analysis with the miniPCR hardware for Genes in Space-6 during Expedition 59. This experiment explored how space radiation damages DNA and how cells repair that ...

The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-1958 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...