Cefiderocol is effective against various gram-negative bacterial infections, with combination therapy offering no clinical advantage over monotherapy.

Mild infections can sometimes occur, leading to issues such as a swimmer’s ear or a hot tub rash. For those with weakened immune systems or those who are already ill, an infection from Pseudomonas can ...

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis, while sparing healthy microbes in the mouse ...

Expert Rev Anti Infect Ther. 2010;8(8):879-885. We recommend a thorough evaluation of patients with non-HACEK Gram-negative endocarditis to assess the necessity of surgical intervention. Decision to ...

Antimicrobial resistance has become one of the greatest threats to public health, with rising resistance to carbapenems being a particular concern due to the lack of effective and safe alternative ...

Gram-negative bacteria deploy a range of protein toxins as mediators of inter-bacterial competition and pathogenicity. Among these, colicins comprise a class of ribosomally synthesised bacteriocins ...

Hospital uptake of newer antibiotics to treat multidrug-resistant gram-negative bacteria was low over a 5-year period, according to a retrospective cohort study. Fully 41.5% of episodes of ...

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut ...

A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem of ...

A mineral-hogging fungus can “bully” bacteria into becoming more antibiotic resistant, according to new work published June 20 in the journal PLOS Biology by Fred Hutch Cancer Center scientists. The ...

A study by LV Prasad Eye Institute highlights rising antimicrobial resistance in post-cataract infections, with aggressive ...