Understand the stages of a standard RNA-seq bioinformatics workflow, including the role of QC, alignment, gene expression quantification, and specialized application analyses Identify key QC metrics ...
The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing (NGS) methods in nonclinical studies to assess the safety risks associated ...
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool to record and dissect gene expression of individual cells in tissues. Compared to bulk RNA-seq, where RNAs from all cells in a ...
High-resolution mapping of active RNA polymerase II transcription initiation provides a dynamic view of gene expression and reveals the entire spectrum of RNA transcripts—from stable mRNAs to ...
Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...
An interdisciplinary team of Rice University researchers has uncovered previously unknown relationships between ...
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