Modulation of the aryl hydrocarbon receptor was associated with significant production of hematopoietic progenitor cells in vitro, according to study results. Perspective from H. Franklin Bunn, MD ...

This is a preview. Log in through your library . Abstract Although erythroid cells and megakaryocytes arise from a common progenitor, their terminal maturation follows very different paths; erythroid ...

Notch pathway is a well-known factor in the development of lymphoid lineage. However, its role in the myeloid lineage has remained ambiguous. We looked into the effect of Notch1 on the megakaryocytic ...

Megakaryocytes are the parent cells that make platelets—sticky bodies that circulate in the bloodstream and help the blood to clot when you get cut. They are also the culprits that contribute to clot ...

Platelets are anucleate blood cells essential for haemostasis and wound healing. They also play roles in inflammation, immunity, development of the lymphatic vasculature, and tumour metastases 1.

Scientists have discovered a new role for estrogen in maintaining health. Drs. Yuka Nagata and Kazuo Todokoro report in the December 1 issue of Genes & Development that the most abundant form of ...

Adult blood contains a mixture of mature cell types, each with specialized functions. Single hematopoietic stem cells (HSCs) have been functionally shown to generate all mature cell types for the ...

Effective biomarkers for malignant mesothelioma (MM) are needed for clinical management and the development of mesothelin-targeted therapies. We evaluated serum megakaryocyte potentiating factor (MPF) ...

Those with an increased risk of bleeding may require platelet transfusion in various medical situations such as after a severe injury or prior to major surgery, to prevent bleeding or excessive blood ...

Effective biomarkers for malignant mesothelioma (MM) are needed for clinical management and the development of mesothelin-targeted therapies. We evaluated serum megakaryocyte potentiating factor (MPF) ...