This is a preview. Log in through your library . Abstract OPA1, a dynamin-related guanosine triphosphatase mutated in dominant optic atrophy, is required for the fusion of mitochondria. Proteolytic ...

Uteroplacental insufficiency and subsequent intrauterine growth retardation (IUGR) affects postnatal metabolism. In juvenile rats, IUGR alters skeletal muscle mitochondrial gene expression and reduces ...

Researchers have found that the RNA-binding protein PUM2 contributes to the accumulation of defective mitochondria, a key feature of the aging process. Targeting PUM2 in old animals protects against ...

Scientists have taken a closer look at how mitochondria are maintained in nondividing cells, such as neurons, with the ultimate goal of developing a better understanding of how to prevent or treat age ...

Like bees breathing life into gardens, providing pollen and making flowers blossom, little cellular machines called mitochondria breathe life into our bodies, buzzing with energy as they produce the ...

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental ...

Discover how CKMT2 controls energy balance and mitochondrial health in skeletal muscles, revealing a new link between metabolism and type 2 diabetes management. Study: Decreased mitochondrial creatine ...

A new study is offering novel insights into the effects of too much salt on certain immune cells. The research reveals how salt can dampen mitochondrial functions, disrupting normal immune cell ...

Like bees breathing life into gardens, providing pollen and making flowers blossom, little cellular machines called mitochondria breathe life into our bodies, buzzing with energy as they produce the ...

A study led by EPFL shows that Urolithin A, a natural compound, can abolish high anxiety in rats by repairing mitochondrial function in their brain cells, specifically in the nucleus accumbens. The ...