Opioids are still widely prescribed, but have limited effectiveness and are associated with serious harms. De-prescribing ...

In the struggle against the opioid epidemic in the United States, any positive news is welcome. The crisis is acute: the last report from the Department of Health and Human Services, in 2014, found ...

The FDA has made several updates to its opioid prescribing information, including new warnings about the possibility for increased pain, which can lead to dangerous adverse reactions such as ...

Most agree that there is no proven benefit from the chronic use of opioids (Vicodin, Oxycontin, Fentanyl) for non-cancer pain. From the Centers for Disease Control and Prevention, studies show nothing ...

In cases of opioid use disorder, short-term medically managed withdrawal (commonly known as detox) and long-term rehabilitation treatments that don’t incorporate continued use of buprenorphine or ...

Prescription painkillers are creating a massive public-health crisis. Since 1990, deaths in the U.S. from unintentional drug overdoses have increased by over 500%. Most of this rise can be attributed ...

Credit: Thinkstock. A warning about opioid-induced hyperalgesia has been added to the prescribing information. The Food and Drug Administration (FDA) has updated the prescribing information for all ...

The U.S. Food and Drug Administration (FDA) issued new labeling requirements for opioid pain medications on Thursday, adding a warning about potential drug-induced reactions such as a rise in pain or ...

The U.S. Food and Drug Administration has approved the first test for assessing the risk of opioid use addiction in specific individuals. It is a prescription-use only genetic laboratory test intended ...

New research suggests that δ-receptor agonists regulate intestinal motility and relieve abdominal pain in a mouse model of irritable bowel syndrome, potentially offering a novel CNS-targeted treatment ...