Drug discovery bottleneck? Cell-free platform screens peptides faster, even in harsh conditions

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...
Phys.org

Scientists reveal structural link for initiation of protein synthesis in bacteria

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...
Yale Environment 360

Yale scientists recode the genome for programmable synthetic proteins

Synthetic biologists from Yale were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed ...
Technology Networks

Cells Put Ribosomes Into “Sleep Mode” During Stress

Under stress, animal cells pair inactive ribosomes into RNA-linked disomes. A ribosomal RNA “kissing loop” joins them, protecting ribosomes and reducing protein synthesis to conserve energy.<br /> ...
The Scientist

Aging Cells Rewire their Protein Factories

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.
AZoLifeSciences on MSN

The life cycle of a protein

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.
Labroots

Giant DNA Viruses Have a Feature Like One in Complex Cells

Genetics tools have advanced significantly in recent decades, and have allowed scientist to sequence all of the genetic ...
The Scientist

Cell-Free DNA: Accelerating Next-Gen mRNA Therapeutics

Galit Meshulam-Simon is the associate director of Commercial Applications at Elegen. COVID-19 brought messenger RNA (mRNA) into the global spotlight, demonstrating its speed, flexibility, and efficacy ...