Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to ...

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was ...

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during reproduction. The map marks a major step in the understanding of genetic ...

Photoluminescence measuring station: Team member Genghua Yan was responsible for many of the measurements in the study. (Courtesy: Forschungszentrum Jülich/Ralf-Uwe Limbach) The remarkably high ...

Recombination between homologous chromosomes is essential for successful meiosis. It drives genetic diversity in germline cells and provides the necessary scaffolding for accurate, balanced ...

The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned interest in the role of recombination in the evolution of this new virus as well as other human ...

Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial A systematic review was conducted in MEDLINE, National Library of Medicine, and ...

Use of an RNA-based HRD signature significantly expands the fraction of patients with prostate cancer who may derive benefit from poly (ADP-ribose) polymerase inhibitors (PARPis) compared with using ...