Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...

One year later, in these Hot Papers, Ramakrishnan's group described the complete structure of the 30S subunit at 3 Angstrom resolution, both isolated and complexed with antibiotics. This information ...

Evidence of human construction work is all around us: on the roads we travel, in the buildings we occupy and now even in outer space. But one form of “human construction” quietly does its job without ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

Life runs on ribosomes. Every cell on earth needs ribosomes to translate genetic information into all the proteins needed for the organism to function—and to in turn make more ribosomes. But ...

At the end of the 1970s, Ada Yonath decided she was going to generate crystal structures of the ribosome using x-ray crystallography to establish the exact location of every atom -- considered an ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

Ribosomes—the tiny factories that build proteins in our cells—don't all work with the same efficiency. Researchers from Japan have discovered that ribosomes actually compete with one another, and ...

Members of NAI’s team at Georgia Tech have a new paper in Molecular Biology and Evolution describing an analysis of ribosomal structure and sequence. Their approach chronicles the ribosome’s evolution ...