Chimeric antigen receptor T cell (CAR-T) therapy is considered one of the landmark achievements of modern medicine. The therapy involves harvesting a patient’s own immune cells, genetically ...
Hepatocellular carcinoma (HCC) is an aggressive and heterogeneous liver cancer with restricted therapy selections and poor diagnosis. Although there have been great advances in genomics, the molecular ...
Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...
Master Scaling Single-Cell Biology. This free webinar series covers multi-omic data integration, spatial datasets, and new AI ...
A comprehensive multi-cancer study by researchers at The University of Texas MD Anderson Cancer Center has revealed that cancer cells within tumors are genetically diverse, yet all carry the same core ...
D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription factor and other regulatory proteins.
Immunosenescence, the progressive aging of the immune system, is characterized by changes in immune cell composition and function that increase susceptibility to disease. However, how biological sex ...
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