Atomic Force Microscopy-based SMFS is widely used due to its high force sensitivity and spatial resolution. In this technique, a biomolecule is attached between a surface and an AFM cantilever. As the ...

What is Single-Molecule Imaging? Single-molecule imaging is a powerful technique that allows researchers to visualize and study individual molecules in real-time. By overcoming the limitations of ...

Mechanical forces play a central role in regulating biological function across length scales, influencing processes such as protein folding and stability, molecular transport, enzymatic activity, and ...

The global development of civilization diseases is a challenge that requires many modern solutions, not only in terms of treatment, but first and foremost in terms of early diagnostics. One of the ...

Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching. In a new Nature Communications study, Columbia Engineering researchers report ...