No. 16 Iowa State's first game away from the friendly confines of Hilton Coliseum will be at a distinctive venue coach T.J. Otzelberger knows well.

Sioux Falls POlice have released details from the shooting that happened on Tuesday, November 4, in Sioux Falls.

After pausing dog surrenders and adoptions, the Sioux Falls Area Humane Society confirmed a case of canine distemper – and ...

Friends, residents and relatives held candles and sang prayers after the fatal shooting of Bonita Keeble on Nov. 4 at ...

SIOUX FALLS, S.D. (Dakota News Now) - One day after the first freezing temperature of the season, eastern South Dakota saw ...

Sioux Falls, South Dakota; Monday, 8 p.m. EST BOTTOM LINE: No. 16 Iowa State will take on Mississippi State at Sanford Pentagon in Sioux Falls, South Dakota. Iowa State went 25-10 overall with a 10-2 ...

Wayne State running back Dawson Forgy ran for a program single-game record 181 yards and five touchdowns in the Wildcats’ ...

Court records state that Tank got into a verbal argument while inside her mother’s car. The dispute escalated when Tank ...

Police in Sioux Falls have publicly identified an 18-year-old man who authorities say is responsible for shooting two people, killing one on Tuesday morning.

Glaucoma remains one of the leading causes of blindness in the United States, often progressing silently until vision loss ...

This show provides an opportunity for the public to meet one-on-one with 24 local artists to learn more about their work.

The city is looking for proposals that would "contribute to the vibrancy of downtown" in the space where the lot currently ...