Acid sphingomyelinase deficiency (ASMD) is a rare lysosomal storage disorder; a new report said that plasma lyso-sphingomyelin levels can be used to not only diagnose the rare disease but also predict ...

Sphingolipids are best known as lipids enriched in membrane microdomains and as signaling mediators. Contreras et al. now ascribe a cofactor function to the sphingolipid SM 18. Starting with the ...

Researchers resent a new molecule for visualizing the sphingomyelin metabolism. This offers prospects for innovative therapeutic approaches in infection research. At the end of the 19th century, the ...

China Pharmaceutical University has prepared and tested sphingomyelin phosphodiesterase (SMPD1; aSMase) inhibitors potentially useful for the treatment of cancer, autoimmune disease, chronic ...

Phase I pharmacokinetic and pharmacodynamic results of novel anti-neutropenic factor for the prevention and treatment of febrile neutropenia. This is an ASCO Meeting Abstract from the 2016 ASCO Annual ...

New fluorescent lipids demonstrate how specialized regions in the cell membrane function, explain researchers in a new report. Researchers in Japan, India and France have found that molecules move ...

Novel trifunctional sphingomyelins (TFSM) can be used to visualise Chlamydia inclusions within infected human cells and enables the detection of native sphingomyelin derivatives in non-infectious ...

Phase I study of the combination of balixafortide (CXCR4 inhibitor) and eribulin in HER2-negative metastatic breast cancer (MBC) patients (pts). This is an ASCO Meeting Abstract from the 2017 ASCO ...