In all eukaryotes, a microtubule-based structure known as the spindle is responsible for accurate chromosome segregation during cell division. Spindle assembly and function require localized ...
The mitotic spindle is positioned with respect to asymmetries in cellular polarity to ensure that the partitioning of genomes is coordinated with the partitioning of developmental determinants. A ...
When a cell divides, it performs a feat of microscopic choreography—duplicating its DNA and depositing it into two new cells. The spindle is the machinery behind that process: It latches onto ...
Researchers at Waseda University in Japan have for the first time directly observed the "molecular motor", called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes ...
Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...
Spindles are responsible for pulling apart your chromosomes when your cells divide. New research confirms a theory that these spindles self-organize and interact with one another much like active ...