Numerous cell surface receptors modulate cellular motile functions through the control of dynamic actin polymerization. The status of cytoplasmic actin is sensed and communicated to the nucleus in ...
A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as ...
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Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.
Researchers uncovered 117 enzymes that modify RNA polymerase II, the key enzyme that transcribes DNA into RNA. The study ...
The central dogma of molecular biology describes the flow of genetic information. It was first described by Francis Crick in 1956 as one-way traffic: as: "DNA makes RNA and RNA makes protein." A ...
DNA, the long polymer curled up inside our cells, is often described as the instructions for life. But those instructions are stored in DNA’s chemical code, and reading that code requires the ...
to the project ‘Targeting transcription elongation to modify the prostate cancer tumor immune micro-environment’ to the research group Transcriptional Rewiring in Cancer led by Harri Itkonen ...
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