Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an ...

This new type of immunotherapy shows promise for treating different cancers including prostate cancer, leukaemia and lung ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Subscribe to our newsletter for the latest sci-tech news updates ...

Our immune system relies on T cells to fight infections. But T cells don't just show up and react—first, they train, get a ...

Fred Hutch Cancer Center scientists have developed an experimental strategy to give genetically engineered CAR T cells help ...

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells — which have lost their cancer-fighting oomph — consume this lactic acid ...

SAN FRANCISCO -- The response rate in metastatic gastroesophageal cancer improved by a relative 50% when patients received experimental activated T cells in addition to standard therapy, according to ...

There’s unexpected movement in the world of cell biology — specifically, with the energy factories known as mitochondria. Ever since they were discovered in the mid-nineteenth century, mitochondria ...

(MEMPHIS, Tenn. – August 20, 2024) Scientists at St. Jude Children’s Research Hospital and Washington University School of Medicine have discovered why the flu vaccine can perform poorly. They found ...

Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...