This image illustrates the chemical structure of a purine molecule, highlighting the numbering of the carbon and nitrogen atoms. The purine structure consists of a pyrimidine ring (positions 1 to 6) ...
While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...
A world-first discovery, published in the journal Science, rewrites our understanding of how cells control the production of DNA’s building blocks - and how this process affects the response to widely ...
Depurination of DNA and RNA sequences is an alteration of the sugar-phosphate backbone in which hydrolysis of a purine base (adenine or guanine) occurs. Synthetic oligonucleotides suffer from such ...
Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...
Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...