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5 Things to Know: 49ers Week 18 Saturday Night Showdown vs. the Seattle Seahawks

The San Francisco 49ers return to Levi's® Stadium in Week 18 to host the Seattle Seahawks on Saturday. Fans can expect a primetime, NFC West showdown featuring massive postseason implications, the debut of the 49ers' Rivalries uniform, Faithful Appreciation Day, and the season-ending K9ers Corgi Cup finale.

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49ers bold predictions for huge Week 18 clash with Seahawks

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Seahawks vs. 49ers 2025 Prediction, Odds, Picks - Jan 3

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Pro Picks: Panthers, Ravens Will Win Their Divisions. 49ers Will Edge Seahawks for NFC's No. 1 Seed

The NFL’s final weekend of the regular season features a winner-take-all game between the Ravens-Steelers and a battle for the NFC’s No. 1 seed between the Seahawks-49ers.

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A Seahawks win over the 49ers isn’t the hope — it’s the expectation

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Seahawks vs. 49ers prediction, pick, odds for Saturday's NFL Week 18 game - 1/3/2026

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George Kittle, Trent Williams listed as questionable for Seahawks showdown

Jake Tonges stepped in for Kittle and delivered a clutch 7/60/1 receiving line against the Bears.

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Seahawks defense faces ultimate test as Macdonald, Shanahan meet again

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Seahawks vs. 49ers prediction, odds, pick for Week 18 NFC West decider

Seahawks and 49ers meet with NFC’s No 1 seed at stake

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49ers offense vs. Seahawks defense is a heavyweight battle worthy of a No. 1 seed decider

After already playing each other once back in Week 1, the Seattle Seahawks and the San Francisco 49ers will do battle once again in Santa Clara to close out the regular season in Week 18.

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Fans excited as 49ers, Seahawks battle for NFC's top seed

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NFL playoff race: Seahawks and 49ers meet with NFC’s No 1 seed at stake

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49ers vs. Seahawks Injury Report – Week 18, 2025

The San Francisco 49ers (12-4) will be monitoring nine players on the injury report, including Christian McCaffrey, heading into their Saturday, Jan. 3 matchup versus the Seattle Seahawks (13-3) at Le...

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Seahawks Get Big 49ers Injury Update Before NFC No. 1 Seed Showdown

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Seahawks bold predictions for NFC West decider against 49ers

6don MSN

49ers host the Bears in a matchup of NFC playoff teams fighting for home-field advantage

The Chicago Bears and San Francisco 49ers both clinched playoff berths last week but have plenty still to play for in the final two weeks.

Sporting News

49ers linked to replacing Nick Bosa after injury to help ease him back to field

There will be multiple names to watch out for, but Matt Johnson of Sportsnaut predicted the 49ers would select Kayden McDonald with the No. 26 pick. McDonald would help the 49ers ease Nick Bosa, Mykel Williams, and others back from injury.

San Francisco 49ers

Power Rankings: Where the 49ers Stand Entering Week 18

Find out where the San Francisco 49ers landed in the latest set of NFL power rankings according to several national outlets following their 42-38 victory over the Chicago Bears.

49ers Webzone

49ers playoff picture: Where San Francisco stands heading into Week 18

NFC West title in Week 18. Here's where San Francisco stands in the playoff picture and what a win over Seattle means for seeding.

3don MSN

Kyle Shanahan thought this call cost the 49ers the game vs. Bears

The San Francisco 49ers clinched a 42-38 victory over the Chicago Bears in Week 17. Both teams went back and forth, trading touchdowns with no clear indication of who would come out on top.

4don MSN

Bears LB carted off the field with concerning injury vs. 49ers

Bears linebacker Noah Sewell had his night ended in the third quarter of the game against the 49ers by an ankle injury.

Sporting News on MSN

NFL picks, predictions for Week 18: Ravens take AFC North from Steelers; 49ers, Broncos clinch home-field advantage

In Sporting News' Week 18 picks, find out which teams clinch a playoff spot and who gets sent home in a pivotal final weekend.

1don MSN

49ers’ George Kittle Doesn’t Hold Back on Seahawks’ Defense

San Francisco 49ers star tight end George Kittle didn't hold back on the Seattle Seahawks' defense before their Week 18 matchup.

Seahawks make a bunch of roster moves ahead of Week 18

The Seattle Seahawks make a bunch of roster moves ahead of Sunday's Week 18 division-deciding game versus the San Francisco 49ers.