San Francisco 49ers defensive coordinator Robert Saleh was clear about the issues that would be created if he used man-to-man ...

Jauan Jennings and Brock Purdy, the 49ers’ seventh-round superstars, are a red-hot tandem entering Saturday night’s game ...

Seattle presents many challenges, but one of the most difficult matchups is with wide receiver Jaxon Smith-Njigba, who isn’t ...

Wednesday was the second practice day of the week for both teams, and both teams produced a practice report that sheds some ...

The San Francisco 49ers are Austen Pleasants' sixth NFL team. The backup lineman went from the shadows to the spotlight in an ...

NFL reporter Steve Wyche and NFL analyst Bucky Brooks discuss how amid injuries the San Francisco 49ers still have a chance ...

Chicago Bears tight end Colston Loveland had a great response to the team's rough loss to the San Francisco 49ers.

Christian McCaffrey is dealing with a stiff back ahead of Week 18. Here's the latest injury update on the 49ers RB.

Teams that have started Sam Darnold have gone 27-6 in the past two seasons. However, the Minnesota Vikings saw Darnold start ...

Mike Florio and Chris Simms dive into the Seattle Seahawks vs. San Francisco 49ers matchup that will decide the winner of the ...

Picking the entire NFL slate in the final two weeks of the season is really challenging. Who is playing? Where's the ...

Bookmakers and bettors are not in total alignment when it comes to one CFP showdown and a huge NFC West tilt. Sammy P reports ...