With the No. 1 seed at stake, the status of multiple 49ers Pro Bowlers is unclear for Saturday's showdown against the ...

No NFL offense has been hotter as of late than that of the San Francisco 49ers, and it's been due in large part to the play ...

There are plenty of candidates to sit atop poll heading in the regular-season finale ... but are any of them worthy of it?

Brock Purdy threw for 303 yards and three touchdowns as San Francisco is now one win away from earning the NFC's top seed.

There is a ton to keep track of for the San Francisco 49ers in Week 18 should they lose to the Seattle Seahawks.

Former Saints quarterback Drew Brees is on a fast track to the Pro Football Hall of Fame — and few would argue otherwise. The ...

OAKLAND — A San Leandro man has been arrested and criminally charged in the hit-and-run death of a bicyclist near the Oakland ...

After losing a 1,300 horsepower race car, I decided it was time for a new direction. That direction somehow involved buying a ...

Frank Gore, who ranks No. 1 in 49ers' rushing history and No. 3 in the NFL record book, is among 15 modern-era finalists for ...

Christian McCaffrey is dealing with an illness in Week 15. We break down what it means for fantasy football decisions.

The San Francisco 49ers (9-4) will face the Tennessee Titans (2-11) in Week 15 at Levi’s Stadium, with all eyes on star running back Christian McCaffrey. McCaffrey was a late addition to the injury ...

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the ...