Cancer cells evade apoptosis by transitioning between cell states of drug-sensitivity. Necroptosis vulnerability state was uncovered, and mathematical models revealed why drug holiday fails, while ...

In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children's Hospital report new evidence that a novel means of boosting the natural immune ...

Diagnosing cancer and selecting the appropriate therapy depend crucially on how well experts understand the processes in ...

Many people confuse shame and guilt, and it is useful to know the difference between the two. The first reason is that shame often masks anger and vice versa. Some chronically angry and raging people ...

A partial government shutdown on Oct. 1 appears likely as Democratic and Republican leaders remain at a stalemate. Key disagreements include the expiration of pandemic-era health insurance subsidies ...

This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, ...

From Santiago Ramón y Cajal’s hand came branches and whorls, spines and webs. Now-famous drawings by the neuroanatomist in the late 19th and early 20th centuries showed, for the first time, the ...

Takeda is tapping out of the cell therapy arena as part of a "strategic portfolio reprioritization," with 137 roles at the drugmaker's Massachusetts R&D site affected. The company is seeking a partner ...

Everyone flirted with 89bio. Only Roche wanted to put a ring on it. In a financial filing, 89bio detailed the path from talks with numerous drugmakers to weeks of negotiations with Roche that ended in ...

The Secret Service has disrupted a sprawling telecommunications network in the New York Tri-State Area that investigators say posed a serious potential disruption to New York's telecom systems and a ...