New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal differentiation ...

A comprehensive analysis has identified novel enhancers associated with neuronal development and disease. An international collaboration of researchers led by Masahito Yoshihara at Chiba University ...

An international team of scientists has made a significant breakthrough in understanding how gene expression is regulated ...

When the Nanog gene (green region) is inactive, one of the three enhancer regions is spatially far away. When active, the same enhancer region makes close contact, interacting with the other enhancers ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

Evgeny Kvon, a geneticist at the University of California, Irvine, fell in love with molecular biology when he learned about the experiments that led to the discovery of DNA as the carrier of genetic ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...