This time, offensive tackle and future Hall of Famer Trent Williams is hurt. According to Dan Graziano of ESPN, the 49ers' ...

The Seattle Seahawks could have some stars returning from injury in Week 18 vs. the San Francisco 49ers, but one injury ...

The San Francisco 49ers received a timely boost as they prepare for a critical showdown against the Seattle Seahawks. With ...

The good news for the 49ers is that they already have clinched a playoff spot. The bad news is that it's going to be ...

The San Francisco 49ers caught a tough injury break involving left tackle Trent Williams during a big game against the ...

The 49ers’ roller coaster of a season that’s now generated very real momentum toward a potential Super Bowl appearance just ...

The San Francisco 49ers received tough news on tight end George Kittle for Sunday's game against the Chicago Bears.

Chicago Bears' linebacker Noah Sewell is believed to have suffered a torn Achilles in Sunday night's loss to the San ...

San Francisco 49ers wide receiver Ricky Pearsall is dealing with an injury in the first half of the Week 17 game against the ...

The Bears walked off the field Sunday night after a 42-38 loss to the 49ers, but that doesn’t seem to be the biggest deal now ...

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a ...

The San Francisco 49ers made two roster moves before Week 17, and one of them may be bad news for TE George Kittle.