After being limited to just four games last season due to multiple injuries, McCaffrey has returned to top form in 2025. He’s ...

The San Francisco 49ers are dealing with multiple significant injury concerns entering their Week 18 showdown against the ...

The San Francisco 49ers have dealt with several key injuries throughout the 2025 season. And yet, this Saturday against the ...

McCaffrey (back) will not practice Tuesday, Matt Barrows of The Athletic reports.

Frank Gore, who ranks No. 1 in 49ers’ rushing history and No. 3 in the NFL record book, is among 15 modern-era finalists for ...

“Huge,” Warner said of the 49ers’ 42-38 win Sunday night against the Chicago Bears. “Hey, one more.” Yep, one more ...

Seattle’s defense dominated. Again. It overcame two more turnovers by quarterback Sam Darnold to beat the Panthers 27-10.

The Bears fell short against the 49ers in a shootout on Sunday night. Our staff shares their thoughts on arguably the NFL's ...

Bears linebacker Noah Sewell had his night ended in the third quarter of the game against the 49ers by an ankle injury.

Brock Purdy threw for 303 yards and three touchdowns as San Francisco is now one win away from earning the NFC's top seed.

The 49ers (11-4) will miss their play-making tight end while at the same time welcome back one of their top receivers when ...

We break down the DraftKings +390 McCaffrey First TD prop and the model's top value bet on the Chicago moneyline.