Heliot Ramos, Rafael Devers and Wilmer Flores homered off Nestor Cortes in the first inning and the San Francisco Giants beat San Diego 4-3 to hand the Padres their fourth straight loss.

Petco Park’s packed house filled the Gaslamp Quarter with a symphony of boos. Ramos proceeded to troll the Padres fans sitting in the left-field bleachers, pointing and laughing at the Friar faithful. The rest of the night, Ramos was greeted with boos every time he stepped to the plate or fielded a fly ball.

Pregame analysis and predictions of the San Francisco Giants vs. San Diego Padres MLB game to be played on August 19, 2025 on ESPN.

The San Francisco Giants got their daunting road trip off to a strong start with a 4-3 win against the San Diego Padres on Monday at Petco Park.

San Diego Padres center fielder Jackson Merrill is out of the Padres lineup against the Giants on Monday after suffering an apparent left ankle injury in Sunday's series finale against the Dodgers.

A sequel one week in the making! The Giants aren’t better than the Padres, but can they make San Diego feel insecure?

Jackson Merrill slugged his ninth home run of the season in the eighth inning to put the finishing touches on the Giants (59-61) defeat. San Diego improved to 68-52 and pulled into a tie with the Dodgers for first place in the NL West.