The Bills are headed to the playoffs, but who will they play? Here's a look at Buffalo's potential playoff opponents.

After moving as close as +450 heading into the Week 16 slate, Allen is now +3000 (30:1) to win the award for the second year in a row. Jacksonville Jaguars' quarterback Trevor Lawrence is one spot behind Allen in fourth on the board at +7500 odds.

The Buffalo Bills finish up the 2025 NFL regular season with a home game against the New York Jets in Week 18. It’s also very likely set to become the final game in their current stadium, Highmark Stadium — which is also lovingly referred to as “The Ralph” after late founding Bills owner Ralph C. Wilson Jr.

The Philadelphia Eagles come in as the NFC East champions, but the Buffalo Bills have work to do to retain their AFC East title when they host this NFL Week 17 matchup. The Eagles (10-5) hit a rough patch and went on a three-game losing skid because of an inconsistent offense but have bounced back to score 60 points in winning their past two games.

Our Eagles vs. Bills picks, odds & expert predictions expect James Cook to have a big rushing and receiving game against Philadelphia on Sunday, December 28.

The Eagles are one of four teams in the NFL that have clinched their division, but could still move up in the playoff standings thanks to their 13-12 win against the Buffalo Bills Sunday. Unfortunately,

Follow along with the Eagles Wire for live updates, scores, and highlights from the massive showdown at Highmark Stadium on Sunday

The Bills host the Jets in the final game of the 2025-26 NFL regular season. Here's how to get the best deals on tickets to the Week 18 game at Highmark Stadium in Buffalo.